skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

Twofold C-H functionalization: palladium-catalyzed ortho arylation of anilides

Brasche, Gordon ; García-Fortanet, Jorge ; Buchwald, Stephen L

Organic letters, 05 June 2008, Vol.10(11), pp.2207-10 [Peer Reviewed Journal]

Full text available

View all versions
Citations Cited by
  • Title:
    Twofold C-H functionalization: palladium-catalyzed ortho arylation of anilides
  • Author: Brasche, Gordon ; García-Fortanet, Jorge ; Buchwald, Stephen L
  • Description: The ortho arylation of anilides to form biphenyls via a twofold C-H functionalization/C-C bond-forming process is described. The oxidative coupling takes place in the presence of 5-10 mol % of Pd(OAc)2, 10-20 mol % of DMSO, and 4-11 equiv of the aryl substrate in TFA under an oxygen atmosphere. No metal-containing cocatalyst is required.
  • Is Part Of: Organic letters, 05 June 2008, Vol.10(11), pp.2207-10
  • Identifier: ISSN: 1523-7060 ; PMID: 18465866 Version:1 ; DOI: 10.1021/ol800619c
  • Subjects: Anilides -- Chemistry ; Carbon -- Chemistry ; Hydrogen -- Chemistry ; Palladium -- Chemistry
  • Language: English
  • Source: MEDLINE/PubMed (U.S. National Library of Medicine)

Searching Remote Databases, Please Wait