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Synthesis and SAR of geminal substitutions at the C5′ carbosugar position of pyrimidine-derived HCV inhibitors

Verma, Vishal A ; Rossman, Randall ; Bennett, Frank ; Chen, Lei ; Gavalas, Stephen ; Girijavallabhan, Vinay ; Huang, Yuhua ; Kim, Seong-Heon ; Kosinski, Aneta ; Pinto, Patrick ; Rizvi, Razia ; Shankar, Bandarpalle ; Tong, Ling ; Velazquez, Francisco ; Venkatraman, Srikanth ; Kozlowski, Joseph ; Maccoss, Malcolm ; Kwong, Cecil D ; Bansal, Namita ; Kezar, Hollis S ; Reynolds, Robert C ; Maddry, Joseph A ; Ananthan, Subramaniam ; Secrist, John A ; Li, Cheng ; Chase, Robert ; Curry, Stephanie ; Huang, Hsueh-Cheng ; Tong, Xiao ; Njoroge, F. George ; Arasappan, Ashok

Bioorganic & Medicinal Chemistry Letters, 15 November 2012, Vol.22(22), pp.6967-6973 [Peer Reviewed Journal]

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