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Efficient propylphosphonic anhydride (®T3P) mediated synthesis of benzothiazoles, benzoxazoles and benzimidazoles

Wen, Xiaoan ; Bakali, Jamal El ; Deprez-Poulain, Rebecca ; Deprez, Benoit

Tetrahedron Letters, 09 May 2012, Vol.53(19), pp.2440-2443 [Peer Reviewed Journal]

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  • Title:
    Efficient propylphosphonic anhydride (®T3P) mediated synthesis of benzothiazoles, benzoxazoles and benzimidazoles
  • Author: Wen, Xiaoan ; Bakali, Jamal El ; Deprez-Poulain, Rebecca ; Deprez, Benoit
  • Description: Propylphosphonic anhydride (®T3P) promotes cyclization of -aminobenzenethiol, -aminophenol, and -phenylenediamine with carboxylic acids under microwave irradiation. The one-pot procedure is efficient and allows short reaction times, easy workup, and good yields. Thus, we describe here a method for quick preparation of benzothiazoles, benzoxazoles and benzimidazoles.
  • Is Part Of: Tetrahedron Letters, 09 May 2012, Vol.53(19), pp.2440-2443
  • Identifier: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2012.03.007
  • Subjects: Benzothiazole ; Benzoxazole ; Benzimidazole ; Propylphosphonic Anhydride (®T3p) ; Benzazole ; Microwave ; Chemistry
  • Language: English
  • Source: ScienceDirect Journals (Elsevier)

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