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Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)

Deng, Hongfeng ; O'Keefe, Heather ; Davie, Christopher P ; Lind, Kenneth E ; Acharya, Raksha A ; Franklin, G Joseph ; Larkin, Jonathan ; Matico, Rosalie ; Neeb, Michael ; Thompson, Monique M ; Lohr, Thomas ; Gross, Jeffrey W ; Centrella, Paolo A ; O'Donovan, Gary K ; Bedard, Katie L Sargent ; Van Vloten, Kurt ; Mataruse, Sibongile ; Skinner

Journal of medicinal chemistry, 23 August 2012, Vol.55(16), pp.7061-79 [Peer Reviewed Journal]

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