skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

Evaluation of bioimpedance spectroscopy for the measurement of body fluid compartment volumes in rats

Hu, Lufei ; Maslanik, Tom ; Zerebeckyj, Mykolai ; Plato, Craig F

Journal of Pharmacological and Toxicological Methods, March 2012, Vol.65(2), pp.75-82 [Peer Reviewed Journal]

Full text available

Citations Cited by
  • Title:
    Evaluation of bioimpedance spectroscopy for the measurement of body fluid compartment volumes in rats
  • Author: Hu, Lufei ; Maslanik, Tom ; Zerebeckyj, Mykolai ; Plato, Craig F
  • Description: Bioimpedance spectroscopy (BIS) has been used in human and large animal research to assess body fluid compartment volumes (BFC) such as total body water (TBW), extracellular fluid volume (ECFV), and intracellular fluid volume (ICFV). To date, the application of BIS for determination of BFC in small research animals has been limited. We sought to evaluate the sensitivity and consistency of BIS for the determination of BFC in male SD rats. Thus, in separate series of experiments, we a) compared BFC values determined using BIS to BFC values obtained using radioisotope indicator dilution methods; b) examined day-to-day intra- and inter-rat BFC variability in small (267.8 ± 5.4 g) and large (372.6 ± 5.6 g) rats (n = 8/group) as compared to empirical normative mammalian values; c) evaluated the sensitivity of BIS to...
  • Is Part Of: Journal of Pharmacological and Toxicological Methods, March 2012, Vol.65(2), pp.75-82
  • Identifier: ISSN: 1056-8719 ; E-ISSN: 1873-488X ; DOI: 10.1016/j.vascn.2012.02.001
  • Subjects: Bioimpedance Spectroscopy ; Body Fluid Compartment Volume ; Extracellular Fluid Volume ; Methods ; Non-Invasive ; Radioisotope ; Rats ; Pharmacy, Therapeutics, & Pharmacology ; Chemistry
  • Language: English
  • Source: ScienceDirect Journals (Elsevier)

Searching Remote Databases, Please Wait